Research references are listed, as nearly as possible, by the dates on which the research was first published or brought into the public domain.
Clicking on the title of the research will take you either to a precis of the findings (with further links to the relevant source material) or directly to that source material.
Because many original research papers remain restricted by publishers it is not always possible to link visitors to the original research so the links that we give will normally be to the 'second level' reports from reliable and respected sources such as MedicalNewsToday, WebMD, MedPage Today and Medscape.
If you wish to pursue your own researches beyond these pages, one of our regular contributors, John Scott, has some suggestions for sites which will provide you with reliable and informative material.
For the latest in helminth research, visit the Open Source Helminth Therapy website
Genetic evidence for worms preventing diseases such as asthma
02/11
Can helminths help cure Crohn's disease?
07/10
The therapeutic helminth?
01/09
The broader implications of the hygiene hypothesis
10/08
The use of Trichuris suis and other helminth therapies
to treat Crohn’s disease
01/07
Helminths may help combat allergic asthma
11/05
The hygiene hypothesis and atopy. Bring back parasites?
01/06
Parasites in the gut have an essential role in developing a healthy immune system
06/10
The worm has turned
11/04
Trichuris suis therapy in Crohn’s disease
04/04
The increased prevalence of allergy and the hygiene hypothesis: missing immune
deviation, reduced immune suppression, or both?
2004
A further paper showing that intestinal worms (helminth parasites) protect mice against anaphylaxis. Journal of Immunology 2004
Intestinal worms may reduce peanut anaphylaxis. Research dating from 2002 suggests that the reaction of mice who have been infected with intestinal parasites (helminths) to peanut IgE (which would normally produce a strong anaphylactic reaction) was significantly reduced, suggesting helminths may effectively block these reactions. Journal of Immunology 2002
Human hookworm infection in the 21st century. Although most of this section of the FM website is devoted to singing the praises of intestinal parasites as immune system modulators, a significant section of the scientiifc and medical community continue to seek ways to eliminate them from the human body on the grounds that, in many parts of the world, parasitic infections cause much ill health and, on occasion, wide spread mortality. This lengthy paper looks in details at parasitic infections worldwide.
Parasites represent a major selective force for interleukin genes and shape the genetic predisposition to autoimmune conditions – 2009
Multiple worms species better for immunoregulation
03/08
Children with early infections of helminths appear to have less allergic disease
- 2008
Studies at University of Nottingham suggest that the louse polyplx serrata triggered an immunosupressive effect in wild mice. 06/09
Helminths and allergic disease in Vietnam
2007
West Coast Crohn's patients on hookworm therapy swear by treatment
(05/09)
Ethiopian study shows that people with hookworm infection only half as likely to wheeze as uninfected people
(03/09)
In a Vietnamese study, individuals with the highest level of hookworm infestation were found to be the least likely to have an allergic response to house dust mites
(03/09)
Pig whipworms (Trichuris suis) found to be safe and effective in the treatment of Inflammatory Bowel Disease, especially Crohn's disease
(03/09)
Parasitic worms and inflammatory diseases
(03/09)
Worms as a treatment for autism 1
(03/09)
Worms as a treatment for autism 2
(03/09)
Parasitic worms may lead to treatment for multiple sclerosis
and
Hook worms in MS trial
(03/09)
A little dirt is good for you!
(03/09)
Are worms vital to human health?
(03/09)
Original paper - safety trial at Nottingham University for hookworm infection in individuals with measurable airway responsiveness but not clinical asthma.
2008
First clinical trails of hookworms to treat Crohn's disease take place at Nottingham University in the UK.
(07/08)
Early experiments with pig whipworms and Crohn's disease by Dr Joel Weinstock at the University of Iowa
(06/08)
Could a gut parasite hold the cure for asthma?
(06/08) via JS
Exploring the causes of immune system meltdown.
(03/08)
Worms - 'drug cabinet' of the future?
(06/06)
Crohn’s disease: a new approach
(02/05)
The increased prevalence of allergy and the hygiene hypothesis: missing immune deviation, reduced immune suppression, or both? SergioRomagnani, Center for Research, Transfer and High Education MCI_DNENT, University of Florence 2004
Articles on helminthic therapies.
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