Coeliac disease and B vitamins

Coeliac disease is a typical example of a malabsorption syndrome which significantly raises the risk of deficiency, including that of folate and vitamin B12, which results in high levels of homocysteine in newly diagnosed coeliacs.

In a study published in the World Journal of Gastroenterology in February, the VUmc University Medical Centre in the Netherlands found that daily supplements of vitamin B6, folate, and vitamin B12 daily had a significant effect on homocysteine levels.

The study reinforces earlier findings that coeliac disease, and its severity, had a marked effect on homocysteine levels and that the regular use of B vitamin supplements resulted in higher vitamin B6, folate and vitamin B12, and lower plasma homocysteine levels.

The full research report


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