Mast cell-mediated allergic disease is involved in many allergic reaction diseases such as anaphylaxis, rhinitis, asthma and atopic dermatitis. A group of scientists from the Department of Pharmacology, School of Medicine, Kyungpook National University, Daegu 700-422, Republic of Korea, has investigated the effect of a water extract of the ripe fruits of Rubus coreanus Miq. (Rosaceaea) (RFRC) (Korean black raspberry) on mast cell-mediated allergic inflammation, and the mechanism of the action, in mice.
Their findings show that RFRC inhibits mast cell-derived allergic inflammatory reactions. Further in vivo and in vitro anti-allergic inflammatory effects provide proof of a possible therapeutic application of Korean black raspberry in allergic inflammatory disease.
Source: International Journal of Molecular Medicine
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