The interaction between omega-3 fatty acids and mast cells has remained largely unknown in allergies, until this study from Daejeon University in Korea. They found that omega-3 alpha-linolenic acid reduced the production of interleukin (secreted proteins that are part of the regulation of the immune system) in mast cells thus reducing the intensity of the allergic reaction. Orally administrated fish oil with high levels of omega-3 fatty acids targeted the mast cells and reduced the severity of dermatitis and thickened the epidermis in an atopic mouse model. The Korean scientists suggest that omega-3 fatty acids may alleviate allergic disease.

Source: The Journal of Nutritional Biochemistry

First Published IN August 2012

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