Anaphylaxis

Please click on the links below to read our articles. If you are interested in research findings, click here for links to research reports.

For links to freefrom food products click here.

Anaphylaxis Campaign Corporate Conference - September 2016
Includes presentations on the EuroPrevall/IFAAM Eurpean work on thresholds (Professor Clare Mills), precautionary allergen labelling and freefrom manufacture– and the Paul Wilson case.

Could an excess of histamine cause anaphylaxis? Dr Janice Joneja was asked whether and excess of histamine in someone who was histamine intolerant? June 2016

AIM, or Anaphylaxis Information Matters – a new awareness raising campaign from the Anaphlyaxis Campaign to sit alongside NICE's new quality standards for allergy care. March 2016

The Anaphylaxis Campaign - 20 years on. Michelle Berreidale-Johnson reports. January 2016

Idiopathic anaphylaxis – could histamine be the cause? December 2015

Needle length - how crucial is it in anaphylaxis? New research suggests it could be the difference between life and death. October 2015

New Epipen case includes sensors to locate a misplaced Epipen, receive alerts, monitor temperature, notify support networks and provide verbal alerts to help bystanderes in an emergency. January 2015

'Allergy shaming' and bullying increases risks for seriously allergic teens. An article on Yohoo health. December 2014

Managing anaphylaxis on a day to day basis. Allergy nurse, Sue Clarke. Part of an Anaphylaxis Campaign conference. November 2014

What do we really know about anaphylaxis? Dr Andrew Clark. Part of an Anaphylaxis Campaign conference. November 2014

Research from the University of Southampton and the Anaphylaxis Campaign suggests that parents of children with severe and multiple allergies are more likely to turn to complementary and alternative medicines 'out of desperation at the failure or absence of local medical provisions and through fear of side effects of conventional medicines' but were unlikely to tell their doctors. They suggest that healthcare professionals should be aware of this and should engage positively with parents and patients in discussions as to the safe use of CAM therapies. November 2014

The Chicago Public School (CPS) system used emergency epinephrine in 38 cases during the 2012-2013 school year and more than half of these cases were for first-time events. Octoebr 2014

Alert5 - emergency alarm app. October 2014

The state of the nation’s understanding of Anaphylaxis. Ruth Holroyd reports on the EAACI meeting. August 2014

Food-Dependent Exercise-Induced Anaphylaxis - Dr Janice Joneja. June 2014

Adrenaline Auto-injectors to be reviewed by the European Medicines Agency. May 2014

Idiopathic anaphylaxis. Guidance for nurses from Nursing in Practice. April 2014

Adrenaline Auto-injectors explained – Ruth Holroyd of What Allergy? discussses the alternatives and describes her own experience of using them. Febaruary 2014.

Food Allergy and Anaphylaxis Connection Team – FAACT. New support and advocacy group in Ohio, USA covering education, civil rights advocacy, government relations etc. Staffed entirely by parents of allergic children. December 2013

Idiopathic anaphylaxis. Helpful new fact sheet on the Anaphylaxis Campaign website on idiopathic allergy – or a reaction for which no trigger has been identified. March 2014

Encouraging story on the What Allergy? blog from mother of an allergic teenager on his first meal out on his own. February 2014

Anaphylaxis Campaign conference – Managing allergies in children and young people – October 2013

Good basic information about epinephrine/adrenalin and how to use it from MedlinePlus.

Peanut allergic California teenager dies despite being treated with three Epipens. September 2013.

Very useful guidance on understanding and diagnosing food anaphylaxis for medical or lay readers from Medscape Pediatrics. July 2013

Advice on how to persuade teens to carry their autoinjectors. August 2013

Anaphylaxis in Children: Current Understanding and Key Issues in Diagnosis and Treatment by Chitra Dinakar, Section of Allergy, Asthma and Immunology, Children’s Mercy Hospital and Clinics, University of Missouri-Kansas City. July 2012

Obese patients need to inject epinephrine/adrenalin lower into the thigh to make sure that they reach muscle. March 2013

Exercise induced anaphylaxis: a clinical view. Detailed article summarising current evidence on pathophysiology, diagnosis and management of exercise induced anaphylaxis from Carolotta Povesi Dascola and Carlo Caffarelli of the Dipartimento di Medicina Clinica e Sperimentale at the Università degli Studi di Parma. September 2012

Will the new Auvi-Q epinephrine/adrenalin injector challenge the Epipen's dominance? It is smaller, slimmer and can 'talk you through' using it in an emergency – could be very helpful when you are panicking. Interesting article in the NY Times – and check out their site.

The EAACI launches a Food Allergy and Anaphylaxis Campaign across Europe to enhance knowledge and awareness of food allergy amongst policy makers and to educate the public how to react in an emergency. February 2013

On average, only 59% of US patients and/or their caregivers carry epinephrine auto-injectors (EpiPens) and, in the case of many of those who do carry EpiPens, their units may have expired. May 2012

Anaphylaxis in Latin America. Main clinical manifestation on the skin causes: drugs (31.2%), foods (23.3%) and insect stings (14.9%) in adults, with foods predominating in children. June 2011

Up to 6% of Americans may have had an anaphylactic allergic reaction – AAAAI meeting report. March 2012

Freddy the Mouse allergy books for small children. August 2011

Allergy within the NHS – a circular problem. Frances Dale explains. October 2011

A great blog by the mother of four-year-old Gabriel who has a multiplicity of life threatening allergies. September 2010

Epinephrine key – new and more convenient delivery. July 2010

A warning about adrenalin/epinephrine injectors from FAAN. May 2010

The hidden menace that can cause death during surgery. How a cough syrup can kill you! Dr Harry Morrow Brown explains how. February 2010

How hard it can be parenting a severely allergic child. February 2010

Is tongue tingling a safe guide to allergenicity? From the US Food Allergy and Anaphylaxis Network. 2009

Anaphylaxis action plan - Ruth Holroyd describes her first experience using an EpiPen and suggests at anaphylaxis action plan. 2009.

Use your EpiPen! Nut-allergic Ruth Holroyd encourages fellow allergics to use their EpiPen. On two occasions she did not – and only just survived... 2009

Moving on to college: how to help teenagers with food allergies and intolerances cope when they leave home for university, by Carole Risinger. 2005

The Case for Desensitisation: Outlining the theory behind desensitisation and the evidence for it as a practical remedy for reducing allergic reaction. Dr Lyndon Mansfield and Dr Harry Morrow-Brown discuss. 2006

Anaphylaxis and Anxiety: A case study for parents dealing with the anxiety that can arise in children living under the threat of a possible anaphylactic reaction – a member of FAAN (US Food Allergy Network). 2006

Dealing with a Reaction at School: A case study of one mother who evaluated her own response and accordingly took sensible measures to reassure her daughter and instruct staff in the event of a recurrence – a member of FAAN (US Food Allergy Network). 2005

 

NB Information on this site is not a substitute for medical advice and no liability can be assumed for its use.

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Research reports

Optimal needle length for an Epinephrine auto-injectors (EAI) for infants weighing 7.5 to 15kg should be shorter than the needle length in current, commercially available pediatric EAI, in order to avoid striking the bone and possible intraosseous injections. March 2016

Anaphylaxis in children and adolescents: The European Anaphylaxis Registry. January 2016

Worrying number of parents do not know how to give an emergency epinephrone or adrenaline shot. January 2016

Food the most common trigger of anaphylaxis in paediatric population but epinephrine underused and children may have several episodes before being assessed by an allergist. November 2015

Wheat-Dependent Exercise-Induced Anaphylaxis. September 2015

Epidemiology of anaphylaxis. Could Vitamin D exposure be relevant? September 2015

Instances of anaphylaxis doubles over seven years in Ontario, Canada. September 2015

Anaphylaxis is underdiagnosed in emergency departments. August 2015

The majority of food allergic children who passed an oral food challenge subsequently ate target food regularly and their family's quality of life improved. Adverse reactions were rare and never serious. August 2015

Even if severe allergic reaction is in doubt, epinephrine should be used. August 2015

Hospitalisation rate for potentially fatal allergic reactions has almost tripled in Australia over the past 13 year. July 2015

Eighteen cases of wheat allergy and wheat-dependent exercise-induced urticaria/anaphylaxis sensitized by hydrolyzed wheat protein in soap. June 2015

How to predict biphasic allergic reactions in children. Children are more likely to have a repeat, delayed anaphylactic reaction from the same allergic cause, depending on the severity of the initial reaction. This study looks at the predictors for this phenomenon. June 2015

Allergic acute coronary syndrome (Kounis syndrome). July 2015

Adrenaline/epinephrine in injector pens can survive freezing. July 2015

Gluten sensitivity does not appear to be relevant in wheat-dependant-exercise induced anaphylaxis. September 2014

First report of anaphyalctic reaction to orange in a toddler. November 2014

Wheat-dependent exercise-induced anaphylaxis following laparoscopic adjustable gastric banding procedure associated with Helicobacter pylori infection. June 2014

Researchers call for more thorough investigation and record keeping of court cases involving food allergy and zero tolerance of fraud within the food chain. December 2014

Only 16% of those prescribed epinephrine for severe allergic reactions in the US use their auto-injector properly, and only 7% of those with metered-dose inhalers for asthma use them in the right way. December 2014

In a study at Aston University, Emerade auto-injectors prove to be very much easier and intuitive to use that comparable Jext or Epipen injectors. December 2014

Emergency departments must understand that adrenaline/epinephrine should be administered as soon as possible in the treatment of an allergic reaction. December 2014

Anaphylaxis caused by linseed in baked bread. July 2014

Treatment of allergic reactions in the emergency setting can be inconsistent and unpredictable, according to the results of a new Food Allergy Research & Education (FARE) survey. September 2014

Oral mite anaphylaxis caused by mite-contaminated okonomiyaki/ pancake-mix in Japan. March 2014

Epinephrine autoinjector training programmme improves care for children in schools and community settings. March 2014

Anaphylaxis to honey. January 2014

Pine nut anaphylaxis - a study of the proteins involved. November 2013

A person with a food allergy is more likely to be murdered than to die from a severe reaction, according to a new study. November 2013

Predictors of epinephrine autoinjector needle length inadequacy. October 2013

Parents of anaphylactic children show different levels of caution depending onthe wording of allergy warnings on foods even though the actual allergy risk may be the same. July 2013

Patients allergic to garlic normally present with dermatitis, rhinitis, asthma, and urticari. However, raw garlic could induce anaphylaxis as the proteins are mainly degraded in heating. July 2012

58% of parents failed to use adrenaline injectors correctly in trial at Imperial College, even though all had been trained in how to use the device. Specialists call for more intuitive design and better training. July 2013

Gelatin-containing sweets can elicit anaphylaxis in a patient with sensitization to galactose-α-1,3-galactose. February 2013

How to encourage food allergic adolescents to use adrenaline. November 2012

Food allergic adolescents are at higher risk of fatal anaphylaxis because they so often fail to carry or use their medication, so require special consideration in designing appropriate management strategies. November 2012

Scientists have developed a test to determine the risk of anaphylaxis in individuals. October 2012

Anaphylaxis induced by inhalation of steam from boiling lentils. July 2012

While raw garlic can cause dermatitis, urticaria, asthma, rhinitis and, rarely, anaphylaxis, it appears that most of the allergens are heat labile and therefore cooked garlic may be well tolerated. August 2012

Individuals bitten in the US by the lone star tick may develop IgE antibodies to the carbohydrate alpha-gal. If they then consume mammalian meat containing alpha-gal, delayed anaphylaxis may follow. July 2012

Protocol for follow up treatment after anaphylactic shock. March 2012

Only one-third of initial food-allergic reactions with symptoms of anaphylaxis were recognised and treated with epinephrine. Fewer than half of patients were referred to allergists. May 2012

Huge rise in potentially fatal allergies. December 2011

Heart failure and anaphylactic shock – two cases. May 2011

New online course teaches people how to prepare for anaphylaxis. August 2010

Insulin and anaphylaxis: desensitisation, a case study. January 2011

Treatment of anaphylaxis: EpiPen, Twinject or another autoinjector? March 2011

Anaphylaxis: a ten years inpatient retrospective study. September 2010

Do EpiPens save lives? June 2011

Anaphylaxis through the eyes of the food allergic child. January 2011

Food allergy – severe reactions may need two shots of epinephrine. March 2010

Unexplained anaphylaxis could be a reaction to meat. February 2009

Why you might need a second dose of epinephrine/adrenaline. November 2009

A paper showing that intestinal worms (helminth parasites) protect mice against anaphylaxis. Journal of Immunology 2004

Sugar-coated polymer is new weapon against allergies and asthma. November 2009

Research advice on using out of date Epipens. May 2009

Launch of the Anapen 500 for heavier anaphylactics. October 2009

Need for more EpiPen training. July 2009

Molecular mechanism of anaphylaxis decoded. March 2009

Chemical clues to anaphylaxis. March 2008

Worms - 'Drug Cabinet' Of The Future? August 2006

Why some people suffer from recurrent episodes of idiopathic anaphylaxis. December 2007

Adolescents' experiences of being food-hypersensitive. October 2007

Worm may be able to prevent anaphylaxis and asthma-like lung inflammation. June 2006

 

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